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  • In other autoimmune conditions such as RA, anti-TNF treatment has been shown to have a restorative effect on Treg59 and further studies in RA have shown that anti-TNF treatment increases FoxP3 expression, thereby augmenting the Treg suppressive function.74,75 The effects of anti-TNF therapy on Treg also provide contrasting results when assessed in different IBD patient cohorts; the results of stud
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