| http://www.w3.org/ns/prov#value | - On the PASI scale, all biologic agents demonstrated efficacy in reducing moderate to severe psoriasis after a 12-week period of use as compared with placebo.18 Biologic agents target the immune system; therefore, patients must be periodically monitored for symptoms of infection and malignancy.19 These therapies are generally considered safe, but rare, serious adverse effects, such as infections, r
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