| http://www.w3.org/ns/prov#value | - -Conversion of L-dopa to DA in the CNS results in increased CNS DA activity and a reduction in Parkinson symptoms.-Increased DA activity in some areas of the brain causes side effects such as hallucinations, psychosis, insomnia and confusion.-After DDC has been inhibited, Catechol O-methyltransferase (COMT) becomes the predominant enzyme that breaks down L-Dopa in the periphery. (N/V/hypotension)
|