| http://www.w3.org/ns/prov#value | - McIlroy et al. [20] showed also an influence of histamine on the Th1/Th2 balance by an upregulation of the Th2 attractants CCL17 and CCL22 and the downregulation of IFN-??-induced IP-10 in immature human MoDC through involvement of H2R. In other cell types, we were able to show that H2R and H4R stimulation led to downregulation of cytokine and chemokine production, e.g. of TNF-??, CXCL8 and IFN-??
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