| http://www.w3.org/ns/prov#value | - WO 91/02807 (Amgen) (=U.S. Pat. No. 5,158,875) discloses a method for refolding IGF-I in the presence of a fused short positively charged leader sequence, in which amino acids, such as lysine, arginine and histidine are fused at the N-terminus of IGF-I. Inclusion bodies are isolated and solubilized with urea.
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