| http://www.w3.org/ns/prov#value | - Moreover, it has been shown that the absence and/or modification of the gut microflora in mice affects the hypothalamic???pituitary???adrenal (HPA) axis response to stress (6, 7) and anxiety behavior (8, 9), which is important given the high comorbidity between functional gastrointestinal disorders and stress-related psychiatric disorders, such as anxiety and depression (10).
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