| http://www.w3.org/ns/prov#value | - A possible advantage of these HIS4 mutant strains is that since they were constructed by the site-specific insertion/deletion method, they are free of secondary mutations which probably exist in Pichia auxotrophic hosts which are produced, for example, by chemical mutagenesis, such as for example GS115 (NRRL Y-15851) and GS190 (NRRL Y-18014).
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