| http://www.w3.org/ns/prov#value | - The leaflets of the aortic valve become thick and calcified and ultimately can limit the ability of blood from being pumped out of the heart, said James D. Flaherty, MD, Northwestern Medicine cardiologist and Northwestern's principal investigator for SALUS. When the narrowing becomes severe, patients develop symptoms such as shortness of breath, fatigue, lightheadedness and chest pain.
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