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For example, if the target is an enzyme and the reaction has the Michaelis???Menten kinetics: where [S] is the concentration of the substrate, [Et] the total concentration of the enzyme, Kcat turnover number, Km Michaelis???Menten constant, a competitive reversible inhibitor I would change the equation (3) into where [I] is the concentration of the inhibitor and Ki the inhibition constant: . [I]/K
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