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Within this system, parameters including pH, glucose, glutamate, glutamine, lactate, Na+, K+, and NH4+ were measured using a Bio??profile 100+ bioanalyzer with an auto??sampler that was integrated with the DASGIP Parallel Bioreactor Control Software via OPC. The validated bioreactor-analyser system allowed for closed loop control of glucose concentrations in the media, leading to improved quality
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