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In a complex with MAP3K8, NFKB1/p105 repressesMAP3K8-induced MAPK signaling; active MAP3K8 is released by proteasome-dependent degradation of NFKB1/p105 summary for NFKB1 Gene: NF-kappaB (nuclear factor-kappa B) is a rapidly acting primary transcription factor found in all cell types.It is involved in cellular responses to stimuli such as cytokines and stress and plays a key role inregulating the
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