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isa:302623303
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The reaction of the maleimide compound of the general formula [V] specifically a dihalomaleimide derivative with an R-substituted indole compound of the general formula [VI] such as 5-fluorindole, in the presence of a base such as ethylmagnesium bromide, or the like, in organic solvents like tetrahydrofuran (THF), benzene, or toluene or combinations thereof, yields a bisindolylmaleimide compound o
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