. "protein including bovine serum albumin (BSA), gelatin, keyhole limpets haemocyanin and the CD1 molecule, or may be a carbohydrate or may be a micelle. [0079] More particularly, the modulation or manipulation of the immune system may be the modulation or manipulation of T-cell effects, such as CD4+, Th0, Th1 and Th2, CD8+ or CD4??? CD8??? (double negative (DN)) T-cells, natural killer (NK) cells, a" . . . .