. . . "In a further embodiment of the present invention, provided is a method of treating a metabolic disease or disorder, comprising administering to a patient in need of said treatment a therapeutically effective amount of a neuropeptide-2 receptor agonist of the formula (I): wherein: X is 4-oxo-6-(1-piperazinyl)-3(4H)-quinazoline-acetic acid (Pqa), Y is H, an acyl moiety, a substituted or unsubstitute" .