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n4bloodjournal.
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IL-12 plays a central role in the immune response by bridging innate resistance and antigen-specific adaptive immunity.1 It is produced from phagocytic cells and antigen-presenting cells, in particular macrophages and dendritic cells, upon stimulation with bacteria, bacterial products such as lipopolysaccharide (LPS), and intracellular parasites.2,3 The well-documented biologic functions of IL-12
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