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FIP200 was reported to interact with multiple proteins, including FAK (Abbi et al., 2002), Pyk2 (Ueda et al., 2000), TSC1 (Gan et al., 2005), p53 (Melkoumian et al., 2005), ASK1, and TRAF2 (Gan et al., 2006), thereby regulating a variety of cellular functions such as cell migration, proliferation, cell size, and apoptosis.
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