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  • Over-expression of Drp1 or OPA1 could partially rescue different aspects of these defects.Huntington's diseaseProgressive loss of striatal and cortical neurons leads to cognitive and motor impairment and eventually death in patients with HD. Whereas multiple genes have been associated with PD and AD, HD is an autosomal dominant disease caused by trinucleotide expansion [cytosine, adenine, and guan
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