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  • vity or detrusor hyperflexia, idiopathic detrusor overactivity or detrusor instability, benign prostatic hyperplasia, and lower urinary tract symptoms, and combinations thereof. [Claim 3] A method for the treatment of a condition or disorder mediated by TRPM8 receptor antagonistic activity, in a mammalian subject, including a human, which comprises administering to a mammal in need of such treatme
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