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  • Over the years, using techniques from computational biology, X-ray crystallography and molecular biology, we developed small molecules including peptide mimics to disable the TNF, Fas, OPG/RANKL/TRAIL and ErbB receptors' functions.Currently, our studies are focused on the structural and molecular basis of OPG/RANKL/TRAIL and activated K-Ras/ErbB receptors' function in breast, lung and pancreatic c
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