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  • Some of these agents include cancer chemotherapeutic drugs (eg, antimetabolites such as methotrexate, mitomycin, daunomycin, 5-fluorouracil, colchicine, and daunorubicin), anti-inflammatory substances, hypo-osmolar drugs, and immunoconjugate (MDX-RA; Medarex Inc, Princeton, NJ) and immunological agents.14- 25 Immune targeting has been investigated using ricin A immunotoxin26 with good effect, but
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