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  • Importantly, TNF?? can directly affect airway epithelial cell production of a number of cytokines and chemokines, including chemokine C-C motif ligand 20 (CCL20) [12], a unique ligand for the chemokine CCR6 which is expressed on circulating immature dendritic cells (DC) [13], and GM-CSF [14], which is important for DC recruitment, survival and differentiation.
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