However, there was a strong indication of an increased risk of adverse outcomes if women delay ANC care independently of treatment available or description of the intervention: the pooled ORs ranged from 2.42 (95% CI 1.27, 4.59; I2 = 78.3%, p = 0.003) for studies reporting treatment with benzathine penicillin G only compared to those reporting treatment with aqueous penicillin to 2.70 (95% CI 1.13