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  • or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.DRUG INTERACTIONSCNS depressants, including alcohol: Possible adverse additive CNS depressant effects (5.1, 7.1)Imipramine: Decreased alertness observed (7.1)Chlorpromazine: Impaired alertness and psychomotor performance observed (7.1)Rifampin: Combination use may decrease effects (7.2)Ketoconazole: Combination use may increase effects (7.2)USE IN
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