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  • ovis called bacille Calmette-Gu??rin (BCG).52 Because of he limited efficacy of BCG vaccination,48,52 the reduced incidence and prevalence of TB, as well as the insensitivity of the PPD skin test in distinguishing vaccine, TB, or other mycobacterium-induced exposure in the developed world, widespread use of the BCG vaccine has decreased.53-56 Several challenges for the prevention and control of TB
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