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  • To further understand the molecular mechanisms leading to PDAC tumor cell death, Project 9 focuses on inhibitory immune-checkpoints receptors such as programmed death 1 (PD1) and its ligand (PD-L1) whose expression have been significantly associated with various types of cancer, including PDAC. Studies are being conducted to best assess anti-PD1 mAb using genetically engineered orthotopic Kras and
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