However, this expression can be short lived, reaching its peak after only 10min, declining to baseline after 3h.5???7Additional synthesis of P-selectin is brought about within 2h by cytokines, such as interleukin-1, tumour necrosis factor-??, and by thrombin, lipopolysaccharide or oxygen radicals.6???8Similarly, upon incubation of platelets with agents such as adenosine or epinephrine, there is in