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  • Morphologically, myofibroblasts are characterized by the presence of a contractile apparatus that contains bundles of actin microfilaments, especially ?-SMA, associated with proteins such as myosin and stress fibers.12 The mechanisms that give origin to the transdifferentiation of myofibroblasts remain unknown; however, the participation of TGF-??1 in this process has been demonstrated. 13 Blockin
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