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  • Bottom, schematic of the beta-globin locus, including five genes and a distal regulatory element known as the locus control region (LCR), Graph modified from [8].Update on fetal hemoglobin gene regulation in hemoglobinopathiesCurr Opin Pediatr. ;23(1):1-8.Figure 2An emerging network of fetal hemoglobin regulationIn the adult stage, the beta-globin gene, engaged in long-range looping interactions w
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