ISSN 0269-3879 Full text not available from this repository. (Request a copy) Official URL: <a href="http://dx.doi.org/10.1002/bmc.167">http://dx.doi.org/10.1002/bmc.167</a> Abstract/Description During the acute phase response (APR) to tissue injury or infection, the liver is responsible for the level of mediators such as cytokines required at the site of inflammation and providing the essential components for wound healing and tissue repair.