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  • The phosphonate radical serves to bind the peptides ionically or adsorptively to biocompatible surfaces of, for example, implants which contain the oxides, e.g. metal surfaces (e.g. titanium or titanium alloys such as TiAl6V4) or cation-containing surfaces, e.g. on amorphous or sintered calcium phosphate (e.g. hydroxy-apatite, bones, teeth) or calcium phosphate cements (e.g. Biocement D).
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