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  • In-vivo studies on experimental acute lung injury (ALI) in animals and in humans also confirmed the anti-inflammatory effects of -adrenergic agonists including significant suppression of proinflammatory mediators and cytokines such as IL-6 and TNF-??, induction of the anti-inflammatory cytokine IL-10, and reduced neutrophil infiltration in the lung [73, 76???78].
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