Fluorescent antinuclear antibody test (FANA): The fluorescent antinuclear antibody test (FANA) is considered a reliable first step for identifying systemic lupus erythematosus and other autoimmune disorders, including scleroderma, Sj???gren's syndrome, Raynaud's disease, juvenile chronic arthritis, rheumatoid arthritis and antiphospholipid antibody syndrome.