Two different antibiotics to kill H. pylori, such as clarithromycin (Biaxin), amoxicillin, tetracycline, or metronidazole (Flagyl)Proton pump inhibitors such as omeprazole (Prilosec), lansoprazole (Prevacid), or esomeprazole (Nexium)Bismuth (the main ingredient in Pepto-Bismol) may be added to help kill the bacteriaIf you have an ulcer without an H. pylori infection, or one that is caused by takin