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  • It responds poorly to treatment with opioid drugs, which are the strongest painkillers and include such drugs as morphine, codeine, and oxycodone (brand name Oxycontin).In the journal Neuron, researchers at Harvard Medical School reported finding a ???master switch??? for the development of neuropathic pain.1 This switch, the Runx1 gene, is expressed only in sensory nerve cells called nociceptive
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