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  • Stimuli such as hypoxia, electrolyte imbalances, caffeine, nicotine, and other drugs can cause other parts of the conduction system to fire before SA node does, setting off an xtra heartbeat called premature ventricular contraction (PCV) or extrasystole. ??? ??? ??? ectopic focus any region of spontaneous firing other than SA node. if SA node is damaged, this may take over governance of the heart
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