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  • It has been shown that after furin cleavage newly exposed basic amino acids at the C-terminus of proteins can be removed by carboxypeptidases, we hypothesized that all additional amino acid derived from the furin cleavage site at the C-terminus of antibody heavy chain can be removed by using a furin cleavage site that consists of exclusively basic amino acids, i.e. R or K. In testing a number of f
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