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  • It is widely accepted that CB2 receptor activation is associated with potent anti-inflammatory responses, including inhibition of the release of inflammatory mediators including nitric oxide and cytokines such as interleukin (IL)-1, tumour necrosis factor (TNF)-?? and IL-6 from both rodent and human microglial [22,23,120,121] and astrocytic [51,122,123] cells and enhanced release of anti-inflammat
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