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  • It will be important to compare the half-lives of TFV-DP in vaginal lymphocytes from macaques with those in women following TFV gel dosing.Drug resistance emergence when antiretroviral prophylaxis fails is a concern, particularly if the intervention includes drugs that are widely used for treatment, as is the case with TFV. Consistent with human data from CAPRISA 004 showing only wild-type virus d
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