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  • Other clinical trials in which oral allergy symptoms to apple and other raw foods were diagnosed with DBPCFCs support a beneficial effect of birch subcutaneous immunotherapy in a subset of subjects. 34, 37 35 Sublingual immunotherapy (SLIT) with birch pollen extract in adults with birch allergic rhinitis did not significantly reduce apple-induced PFAS symptoms .38The beneficial effects on PFAS wer
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