It has been implicated in working memory, cognitive processes, affective disorders such as schizophrenia, and mediates the primary effects of hallucinogenic drugs. 25I-NBOMe, a derivative of the phenethylamine hallucinogen 2C-I, is a highly potent agonist for the human 5-HT2A receptor with a Ki value of 0.044 nM, making it 16-fold more potent than 2C-I. A radiolabelled form of 25I-NBOMe has been u