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  • Dyslipidemia, and particularly low HDL-C level,45 is a known risk factor for cerebrovascular disease, and treatment with lipid-lowering medications can prevent stroke.46 Stroke is associated with higher AD risk.38 Stroke may interact with amyloid pathology in an additive way and lower the amyloid burden necessary to precipitate dementia.47 Low concentrations of HDL-C are known to be independent ri
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