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  • An erythropoietin or EPO is a protein comprising a native mammalian EPO (e.g., human) or a polypeptide sequence comparable to a native mammalian EPO. As used herein, an EPO analog, fragment, or variant shares a substantial amino acid sequence similarity with a native EPO, as well as at least one biological activity with the native EPO, such as binding to the EPO receptor.
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