ples); (iv) there are additional, new cannabinoid targets distinct from the CB1/CB2 receptors276-278 which do not cause psychoactivity; (v) there are cannabinoids, such as CBD, which do not cause psychoactivity, but have various therapeutic effects.The endocannabinoid system is a very complex one and regulates numerous processes, in parallel with other wellknown systems, such as the adrenergic, ch