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  • provided that when R3 and R4 taken together with adjacent atoms form optionally substituted benzene ring, R1 is a group represented by the formula: ???Y1???Y2???Y3???Ra wherein Y1 is single bond; Y3 is optionally substituted alkylene; Y2 is ???NRb???C(???O)???, ???C(???O)???NRb???; Ra is optionally substituted carbocyclic group, optionally substituted heterocyclic group; and Rb is hydrogen or opti
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