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  • Apart from their direct chemotactic activity, HNPs, by activating as yet unidentified activating receptors, also induce the expression of cytokines and chemokines including IL-1, TNF, IL-8 and monocyte chemoattractant protein-1 (MCP-1) 3.In addition to their numerous roles in innate immunity, it is apparent that HNPs can also galvanize adaptive immune responses by inducing the maturation of DCs an
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