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  • The endotoxin used for this study is obtained from the National Institutes of Health, and is called Clinical Center Reference Endotoxin, or CCRE. The purpose of this Phase 1 research study is to identify a dose of inhaled endotoxin that is safe (does not cause prolonged cough, shortness of breath or other problems), but causes changes in your sputum cell samples that the scientists can measure.
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