Sometimes the medicines used to treat rheumatoid arthritis, especially methotrexate, may result in lung disease.SymptomsChest painCoughFeverShortness of breathOther symptoms that may occur with this disease include:Joint painJoint stiffnessJoint swellingSkin nodulesExams and TestsThe doctor may hear crackles (rales) when listening to the lungs with a stethoscope.