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  • Variance in the activity of cytochrome p450 can lead to abnormal drug metabolism and are associated with potential drug-drug interactions and treatment emergent side effects, Abilify, Strattera, Remeron, Effexor, Paxil, Prozac and Cymbalta are examples of drugs primarily metabolized by the 2D6 enzyme, Poor metabolizers (2D6 PM) are at risk of Abilify-induced akathesia and dosage reductions of
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