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  • Delivery systems, particulate adjuvants and emulsions including alum [4], water-in-oil and oil-in-water emulsions (i.e., Complete Freund???s Adjuvant (CFA) [5] or MF59 [6]) are thought to generate an antigen depot at the site of injection, which is then slowly released over time (although other factors have been described to contribute to the effect of alum and MF59, for example [7,8]).
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