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  • Together, these findings suggest that cagPAI-positive H. pylori directly induces AID expression via NF-??B activation, and that the proinflammatory response caused by H. pylori infection also triggers AID expression via the activation of NF-??B in gastric epithelium, because proinflammatory cytokines, such as TNF-??, can induce NF-??B activation in various types of cells.
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